Samantha is one of India's most sought-after actresses, making her Hindi debut in The Family Man 2 with Manoj Bajpayee. She now has a huge fan base across the country. She will next be seen in the Indian adaptation of the Russo Brothers' multi-series Citadel, directed by Raj & DK in India, alongside Varun Dhawan.

After receiving a diagnosis of the autoimmune condition myositis, Samantha Ruth Prabhu made the decision to prioritize her health by taking a one-year hiatus from employment. Samantha addressed her plans during a recent Instagram live session, denying persistent rumours that she would star with Salman Khan in a Karan Johar production in her Hindi film debut.

Currently, Samantha is on a break from work. She made the decision to break away from acting for at least six months after the Citadel filming was completed. After a busy year, it is said that the actress wishes to concentrate on her health.